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Annotations - 14264

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Original Filename: SGD_features.tab

File Size: 3.17 MB

Created By: admin

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Parent Assembly: GLBRC Y22-3 ( GCA_001634645.1 )

State: complete

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loading - 2016-11-08 12:44:17 -0500
Loading 16454 datapoints - 2016-11-08 12:44:17 -0500
Loaded 6195 of 16454 datapoints - 2016-11-08 12:44:41 -0500



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{"f"=>"10043", "k"=>"10801", "annotation"=>"16", "annotation_term"=>"description", "id"=>"1", "header"=>"false", "skip"=>"true"}

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  SGD:S000002143	ORF	Dubious	YAL069W			chromosome 1		1	335	649	W		1996-07-31	1996-07-31	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data
SGD:S000031098	CDS					YAL069W		1	335	649	W		1996-07-31	1996-07-31	
SGD:S000028594	ORF	Dubious	YAL068W-A			chromosome 1		1	538	792	W		2003-07-29	2003-07-29	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
SGD:S000031372	CDS					YAL068W-A		1	538	792	W		2003-07-29	2003-07-29	
SGD:S000121252	ARS		ARS102		ARSI-1	chromosome 1		1	707	776			2014-11-18	2014-11-18|2007-03-07	Autonomously Replicating Sequence
SGD:S000028862	telomere		TEL01L			chromosome 1		1	801	1	C	-64	2003-09-09	2003-09-09	Telomeric region on the left arm of Chromosome I; composed of an X element core sequence, X element combinatorial repeats, and a short terminal stretch of telomeric repeats
SGD:S000028864	telomeric_repeat					TEL01L		1	62	1	C		2003-09-09	2003-09-09	Terminal telomeric repeats on the left arm of Chromosome I
SGD:S000028865	X_element					TEL01L		1	801	337	C		2003-09-09	2003-09-09	Telomeric X element Core sequence on the left arm of Chromosome I; contains an ARS consensus sequence, an Abf1p binding site consensus sequence and two small overlapping ORFs (YAL068W-A and YAL069W)
SGD:S000028866	X_element_combinatorial_repeat					TEL01L		1	336	63	C		2003-09-09	2003-09-09	Telomeric X element combinatorial repeat on the left arm of Chr I; contains repeats of the D, C, B and A types, as well as Tbf1p binding sites; formerly called SubTelomeric Repeats
SGD:S000002142	ORF	Verified	YAL068C	PAU8	seripauperin PAU8	chromosome 1		1	2169	1807	C		1996-07-31	1996-07-31	Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions
SGD:S000030944	CDS					YAL068C		1	2169	1807	C		1996-07-31	1996-07-31	
SGD:S000028593	ORF	Uncharacterized	YAL067W-A			chromosome 1		1	2480	2707	W		2003-07-29	2003-07-29	Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
SGD:S000031368	CDS					YAL067W-A		1	2480	2707	W		2003-07-29	2003-07-29	
SGD:S000121253	ARS		ARS103		ARSI-8	chromosome 1		1	7997	8547			2011-02-03	2007-03-07	Autonomously Replicating Sequence; replication origin of very weak function
SGD:S000000062	ORF	Verified	YAL067C	SEO1	putative permease SEO1	chromosome 1	L000003363	1	9016	7235	C		2011-02-03	1996-07-31	Putative permease; member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide
SGD:S000029932	CDS					YAL067C		1	9016	7235	C		2011-02-03	1996-07-31	
SGD:S000000061	ORF	Dubious	YAL066W			chromosome 1		1	10091	10399	W		2011-02-03	1996-07-31	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data
SGD:S000029887	CDS					YAL066W		1	10091	10399	W		2011-02-03	1996-07-31	
SGD:S000001817	ORF	Uncharacterized	YAL065C			chromosome 1		1	11951	11565	C		2011-02-03	1996-07-31	Putative protein of unknown function; shows sequence similarity to FLO1 and other flocculins
SGD:S000037154	CDS					YAL065C		1	11951	11565	C		2011-02-03	1996-07-31	
SGD:S000002141	ORF	Uncharacterized	YAL064W-B			chromosome 1		1	12046	12426	W		2011-02-03	1999-07-17	Fungal-specific protein of unknown function
SGD:S000034793	CDS					YAL064W-B		1	12046	12426	W		2011-02-03	1999-07-17	
SGD:S000002140	ORF	Uncharacterized	YAL064C-A	TDA8	YAL065C-A	chromosome 1		1	13743	13363	C		2011-02-03	1996-07-31	Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene
SGD:S000031541	CDS					YAL064C-A		1	13743	13363	C		2011-02-03	1996-07-31	
SGD:S000000060	ORF	Verified	YAL064W			chromosome 1		1	21566	21850	W		2011-02-03	1996-07-31|2011-02-03	Protein of unknown function; may interact with ribosomes, based on co-purification experiments
SGD:S000037087	CDS					YAL064W		1	21566	21850	W		2011-02-03	1996-07-31|2011-02-03	
SGD:S000006787	long_terminal_repeat		YALWdelta1			chromosome 1		1	22230	22552	W		2011-02-03	2000-05-19	Ty1 LTR
SGD:S000028813	ORF	Uncharacterized	YAL063C-A			chromosome 1		1	22685	22395	C		2011-02-03	2003-07-29	Putative protein of unknown function; identified by expression profiling and mass spectrometry
SGD:S000033613	CDS					YAL063C-A		1	22685	22395	C		2011-02-03	2003-07-29	
SGD:S000000059	ORF	Verified	YAL063C	FLO9	flocculin FLO9	chromosome 1	L000003331	1	27968	24000	C		2011-02-03	1996-07-31	Lectin-like protein with similarity to Flo1p; thought to be expressed and involved in flocculation
SGD:S000036982	CDS					YAL063C		1	27968	24000	C		2011-02-03	1996-07-31	
SGD:S000118317	ARS		ARS104		ARSI-31	chromosome 1		1	30946	31183			2011-02-03	2006-08-30	Autonomously Replicating Sequence
SGD:S000178034	ARS_consensus_sequence					ARS104		1	31002	31018	W		2014-11-18	2014-11-18	
SGD:S000000058	ORF	Verified	YAL062W	GDH3	glutamate dehydrogenase (NADP(+)) GDH3|FUN51	chromosome 1	L000000698	1	31567	32940	W		2011-02-03	1996-07-31	NADP(+)-dependent glutamate dehydrogenase; synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; GDH3 has a paralog, GDH1, that arose from the whole genome duplication
SGD:S000036963	CDS					YAL062W		1	31567	32940	W		2011-02-03	1996-07-31	
SGD:S000000057	ORF	Uncharacterized	YAL061W	BDH2	putative dehydrogenase BDH2	chromosome 1		1	33448	34701	W		2011-02-03	1996-07-31	Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3
SGD:S000036902	CDS					YAL061W		1	33448	34701	W		2011-02-03	1996-07-31	
SGD:S000000056	ORF	Verified	YAL060W	BDH1	(R,R)-butanediol dehydrogenase|BDH	chromosome 1		1	35155	36303	W		2011-02-03	1996-07-31|2011-02-03	NAD-dependent (R,R)-butanediol dehydrogenase; catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source
SGD:S000036089	CDS					YAL060W		1	35155	36303	W		2011-02-03	1996-07-31|2011-02-03	
SGD:S000000055	ORF	Verified	YAL059W	ECM1		chromosome 1	L000003052	1	36509	37147	W		2011-02-03	1996-07-31|2011-02-03	Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm
SGD:S000035122	CDS					YAL059W		1	36509	37147	W		2011-02-03	1996-07-31|2011-02-03	
SGD:S000028734	ORF	Dubious	YAL059C-A			chromosome 1		1	36918	36496	C		2011-02-03	2003-07-29|2011-02-03	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified gene ECM1/YAL059W
SGD:S000033378	CDS					YAL059C-A		1	36918	36496	C		2011-02-03	2003-07-29|2011-02-03	
SGD:S000000054	ORF	Verified	YAL058W	CNE1	calnexin|FUN48	chromosome 1	L000000373	1	37464	38972	W		2011-02-03	1996-07-31	Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast
SGD:S000034933	CDS					YAL058W		1	37464	38972	W		2011-02-03	1996-07-31	
SGD:S000002139	ORF	Dubious	YAL056C-A		YAL058C-A	chromosome 1		1	39046	38696	C		2011-02-03	1996-07-31	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data
SGD:S000035879	CDS					YAL056C-A		1	39046	38696	C		2011-02-03	1996-07-31	
SGD:S000000052	ORF	Verified	YAL056W	GPB2	KRH1	chromosome 1		1	39259	41901	W		2011-02-03	2004-01-20|1996-07-31|2011-02-03	Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole genome duplication
SGD:S000033885	CDS					YAL056W		1	39259	41901	W		2011-02-03	2004-01-20|1996-07-31|2011-02-03	
SGD:S000121254	ARS		ARS105		ARSI-42	chromosome 1		1	41992	42151			2014-11-18	2014-11-18|2007-03-07	Autonomously Replicating Sequence

  

Loaded Annotations

Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Feature Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Annotation Term Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Value
UTP10 description Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA; mutant has increased aneuploidy tolerance
PAM16 description Subunit of the import motor (PAM complex); the PAM complex is a component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains a J-like domain
CHS6 description Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex that mediates export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; primary component of the Chs5/6 complex that binds directly to membranes; CHS6 has a paralog, BCH2, that arose from the whole genome duplication
TOK1 description Outward-rectifier potassium channel of the plasma membrane; has two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin
KAR2 description ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p
HCA4 description DEAD box RNA helicase; component of the SSU; interacts with Bfr2p and Enp2p; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis
BET4 description Alpha subunit of Type II geranylgeranyltransferase; required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p
MAD2 description Component of the spindle-assembly checkpoint complex; delays onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability
VPS53 description Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; required for vacuolar protein sorting; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p; human ortholog is implicated in progressive cerebello-cerebral atrophy type 2 (PCCA2)
RNR2 description Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits; RNR2 has a paralog, RNR4, that arose from the whole genome duplication
RRN7 description Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p
APS3 description Small subunit of the clathrin-associated adaptor complex AP-3; involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function; protein abundance increases in response to DNA replication stress
PET130 description Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
BBC1 description Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches
CCT7 description Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; mutant has increased aneuploidy tolerance
IME2 description Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant
ELO1 description Elongase I, medium-chain acyl elongase; catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; ELO1 has a paralog, ELO2, that arose from the whole genome duplication
SET2 description Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes; associates with the C-terminal domain(CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to the cytosol in response to hypoxia
ERG20 description Farnesyl pyrophosphate synthetase; has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis
QCR8 description Subunit 8 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p
HAL5 description Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication
TPK1 description cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication
JJJ2 description Protein of unknown function; contains a J-domain, which is a region with homology to the E. coli DnaJ protein
FMP33 description Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
PIR5 description Putative protein of unknown function; member of the PIR (Proteins with Internal Repeats) family of cell wall proteins; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, and mCherry fusion localizes to the vacuole; non-essential gene that is required for sporulation; mRNA is weakly cell cycle regulated, peaking in mitosis; YJL160C has a paralog, PIR1, that arose from the whole genome duplication
CIS3 description Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
FAR1 description CDK inhibitor and nuclear anchor; during the cell cycle Far1p sequesters the GEF Cdc24p in the nucleus; phosphorylation by Cdc28p-Cln results in SCFCdc4 complex-mediated ubiquitin-dependent degradation, releasing Cdc24p for export and activation of GTPase Cdc42p; in response to pheromone, phosphorylation of Far1p by MAPK Fus3p results in association with, and inhibition of Cdc28p-Cln, as well as Msn5p mediated nuclear export of Far1p-Cdc24p, targeting Cdc24p to polarity sites
SSY5 description Serine protease of SPS plasma membrane amino acid sensor system; contains an inhibitory domain that dissociates in response to extracellular amino acids, freeing a catalytic domain to activate transcription factor Stp1p; other members are Ssy1p and Ptr3p
OPT1 description Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family
PEX2 description RING-finger peroxin and E3 ubiquitin ligase; peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import