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Original Filename: SGD_features.tab

File Size: 3.17 MB

Created By: admin

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Parent Assembly: GLBRC Y22-3 ( GCA_001634645.1 )

State: complete

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loading - 2016-11-08 12:44:17 -0500
Loading 16454 datapoints - 2016-11-08 12:44:17 -0500
Loaded 6195 of 16454 datapoints - 2016-11-08 12:44:41 -0500



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{"f"=>"10043", "k"=>"10801", "annotation"=>"16", "annotation_term"=>"description", "id"=>"1", "header"=>"false", "skip"=>"true"}

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  SGD:S000002143	ORF	Dubious	YAL069W			chromosome 1		1	335	649	W		1996-07-31	1996-07-31	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data
SGD:S000031098	CDS					YAL069W		1	335	649	W		1996-07-31	1996-07-31	
SGD:S000028594	ORF	Dubious	YAL068W-A			chromosome 1		1	538	792	W		2003-07-29	2003-07-29	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
SGD:S000031372	CDS					YAL068W-A		1	538	792	W		2003-07-29	2003-07-29	
SGD:S000121252	ARS		ARS102		ARSI-1	chromosome 1		1	707	776			2014-11-18	2014-11-18|2007-03-07	Autonomously Replicating Sequence
SGD:S000028862	telomere		TEL01L			chromosome 1		1	801	1	C	-64	2003-09-09	2003-09-09	Telomeric region on the left arm of Chromosome I; composed of an X element core sequence, X element combinatorial repeats, and a short terminal stretch of telomeric repeats
SGD:S000028864	telomeric_repeat					TEL01L		1	62	1	C		2003-09-09	2003-09-09	Terminal telomeric repeats on the left arm of Chromosome I
SGD:S000028865	X_element					TEL01L		1	801	337	C		2003-09-09	2003-09-09	Telomeric X element Core sequence on the left arm of Chromosome I; contains an ARS consensus sequence, an Abf1p binding site consensus sequence and two small overlapping ORFs (YAL068W-A and YAL069W)
SGD:S000028866	X_element_combinatorial_repeat					TEL01L		1	336	63	C		2003-09-09	2003-09-09	Telomeric X element combinatorial repeat on the left arm of Chr I; contains repeats of the D, C, B and A types, as well as Tbf1p binding sites; formerly called SubTelomeric Repeats
SGD:S000002142	ORF	Verified	YAL068C	PAU8	seripauperin PAU8	chromosome 1		1	2169	1807	C		1996-07-31	1996-07-31	Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions
SGD:S000030944	CDS					YAL068C		1	2169	1807	C		1996-07-31	1996-07-31	
SGD:S000028593	ORF	Uncharacterized	YAL067W-A			chromosome 1		1	2480	2707	W		2003-07-29	2003-07-29	Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
SGD:S000031368	CDS					YAL067W-A		1	2480	2707	W		2003-07-29	2003-07-29	
SGD:S000121253	ARS		ARS103		ARSI-8	chromosome 1		1	7997	8547			2011-02-03	2007-03-07	Autonomously Replicating Sequence; replication origin of very weak function
SGD:S000000062	ORF	Verified	YAL067C	SEO1	putative permease SEO1	chromosome 1	L000003363	1	9016	7235	C		2011-02-03	1996-07-31	Putative permease; member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide
SGD:S000029932	CDS					YAL067C		1	9016	7235	C		2011-02-03	1996-07-31	
SGD:S000000061	ORF	Dubious	YAL066W			chromosome 1		1	10091	10399	W		2011-02-03	1996-07-31	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data
SGD:S000029887	CDS					YAL066W		1	10091	10399	W		2011-02-03	1996-07-31	
SGD:S000001817	ORF	Uncharacterized	YAL065C			chromosome 1		1	11951	11565	C		2011-02-03	1996-07-31	Putative protein of unknown function; shows sequence similarity to FLO1 and other flocculins
SGD:S000037154	CDS					YAL065C		1	11951	11565	C		2011-02-03	1996-07-31	
SGD:S000002141	ORF	Uncharacterized	YAL064W-B			chromosome 1		1	12046	12426	W		2011-02-03	1999-07-17	Fungal-specific protein of unknown function
SGD:S000034793	CDS					YAL064W-B		1	12046	12426	W		2011-02-03	1999-07-17	
SGD:S000002140	ORF	Uncharacterized	YAL064C-A	TDA8	YAL065C-A	chromosome 1		1	13743	13363	C		2011-02-03	1996-07-31	Putative protein of unknown function; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene
SGD:S000031541	CDS					YAL064C-A		1	13743	13363	C		2011-02-03	1996-07-31	
SGD:S000000060	ORF	Verified	YAL064W			chromosome 1		1	21566	21850	W		2011-02-03	1996-07-31|2011-02-03	Protein of unknown function; may interact with ribosomes, based on co-purification experiments
SGD:S000037087	CDS					YAL064W		1	21566	21850	W		2011-02-03	1996-07-31|2011-02-03	
SGD:S000006787	long_terminal_repeat		YALWdelta1			chromosome 1		1	22230	22552	W		2011-02-03	2000-05-19	Ty1 LTR
SGD:S000028813	ORF	Uncharacterized	YAL063C-A			chromosome 1		1	22685	22395	C		2011-02-03	2003-07-29	Putative protein of unknown function; identified by expression profiling and mass spectrometry
SGD:S000033613	CDS					YAL063C-A		1	22685	22395	C		2011-02-03	2003-07-29	
SGD:S000000059	ORF	Verified	YAL063C	FLO9	flocculin FLO9	chromosome 1	L000003331	1	27968	24000	C		2011-02-03	1996-07-31	Lectin-like protein with similarity to Flo1p; thought to be expressed and involved in flocculation
SGD:S000036982	CDS					YAL063C		1	27968	24000	C		2011-02-03	1996-07-31	
SGD:S000118317	ARS		ARS104		ARSI-31	chromosome 1		1	30946	31183			2011-02-03	2006-08-30	Autonomously Replicating Sequence
SGD:S000178034	ARS_consensus_sequence					ARS104		1	31002	31018	W		2014-11-18	2014-11-18	
SGD:S000000058	ORF	Verified	YAL062W	GDH3	glutamate dehydrogenase (NADP(+)) GDH3|FUN51	chromosome 1	L000000698	1	31567	32940	W		2011-02-03	1996-07-31	NADP(+)-dependent glutamate dehydrogenase; synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; GDH3 has a paralog, GDH1, that arose from the whole genome duplication
SGD:S000036963	CDS					YAL062W		1	31567	32940	W		2011-02-03	1996-07-31	
SGD:S000000057	ORF	Uncharacterized	YAL061W	BDH2	putative dehydrogenase BDH2	chromosome 1		1	33448	34701	W		2011-02-03	1996-07-31	Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3
SGD:S000036902	CDS					YAL061W		1	33448	34701	W		2011-02-03	1996-07-31	
SGD:S000000056	ORF	Verified	YAL060W	BDH1	(R,R)-butanediol dehydrogenase|BDH	chromosome 1		1	35155	36303	W		2011-02-03	1996-07-31|2011-02-03	NAD-dependent (R,R)-butanediol dehydrogenase; catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source
SGD:S000036089	CDS					YAL060W		1	35155	36303	W		2011-02-03	1996-07-31|2011-02-03	
SGD:S000000055	ORF	Verified	YAL059W	ECM1		chromosome 1	L000003052	1	36509	37147	W		2011-02-03	1996-07-31|2011-02-03	Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm
SGD:S000035122	CDS					YAL059W		1	36509	37147	W		2011-02-03	1996-07-31|2011-02-03	
SGD:S000028734	ORF	Dubious	YAL059C-A			chromosome 1		1	36918	36496	C		2011-02-03	2003-07-29|2011-02-03	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified gene ECM1/YAL059W
SGD:S000033378	CDS					YAL059C-A		1	36918	36496	C		2011-02-03	2003-07-29|2011-02-03	
SGD:S000000054	ORF	Verified	YAL058W	CNE1	calnexin|FUN48	chromosome 1	L000000373	1	37464	38972	W		2011-02-03	1996-07-31	Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast
SGD:S000034933	CDS					YAL058W		1	37464	38972	W		2011-02-03	1996-07-31	
SGD:S000002139	ORF	Dubious	YAL056C-A		YAL058C-A	chromosome 1		1	39046	38696	C		2011-02-03	1996-07-31	Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data
SGD:S000035879	CDS					YAL056C-A		1	39046	38696	C		2011-02-03	1996-07-31	
SGD:S000000052	ORF	Verified	YAL056W	GPB2	KRH1	chromosome 1		1	39259	41901	W		2011-02-03	2004-01-20|1996-07-31|2011-02-03	Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole genome duplication
SGD:S000033885	CDS					YAL056W		1	39259	41901	W		2011-02-03	2004-01-20|1996-07-31|2011-02-03	
SGD:S000121254	ARS		ARS105		ARSI-42	chromosome 1		1	41992	42151			2014-11-18	2014-11-18|2007-03-07	Autonomously Replicating Sequence

  

Loaded Annotations

Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Feature Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Annotation Term Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Value
CBP1 description Mitochondrial protein, regulator of COB mRNA stability and translation; interacts with the 5'-untranslated region of the COB mRNA; found in a complex at the inner membrane along with Pet309p; localizes to mitochondrial foci upon DNA replication stress
NUC1 description Major mitochondrial nuclease; has RNAse and DNA endo- and exonucleolytic activities; roles in mitochondrial recombination, apoptosis and maintenance of polyploidy; involved in fragmentation of genomic DNA during PND (programmed nuclear destruction); encodes ortholog of mammalian endoG
LAA1 description AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene
NCE101 description Protein of unknown function; involved in secretion of proteins that lack classical secretory signal sequences; SWAT-GFP and mCherry fusion proteins localize to the cytosol
RCY1 description F-box protein involved in recycling endocytosed proteins; involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth; direct interaction with C-terminal cytoplasmic region of Drs2p plays an important role for Drs2p function in endocytic recycling pathway
PRP21 description Subunit of the SF3a splicing factor complex; required for spliceosome assembly
ECM25 description Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p
ACO2 description Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
MBB1 description Putative protein of unknown function; conserved among S. cerevisiae strains, not conserved in closely related Saccharomyces species; protein detected in large-scale protein-protein interaction studies; YJL199C is not an essential gene
PHO90 description Low-affinity phosphate transporter; acts upstream of Pho81p in regulation of the PHO pathway; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth; PHO90 has a paralog, PHO87, that arose from the whole genome duplication
UBP12 description Ubiquitin-specific protease; cleaves ubiquitin from ubiquitinated proteins; present in the nucleus and cytoplasm
CDC6 description Essential ATP-binding protein required for DNA replication; component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p; relocalizes from nucleus to cytoplasm upon DNA replication stress; degraded in response to plasma membrane stress
SOP4 description ER-membrane protein; subunit of evolutionarily conserved EMC (Endoplasmic Reticulum Membrane Complex) implicated in ERAD (ER-associated degradation) and proper assembly of multi-pass transmembrane (TM) proteins; EMC acts in yeast as an ER-mitochondria tether that interacts with outer membrane protein Tom5 of TOM (Translocase of the Mitochondrial Outer Membrane) complex; suppressor of pma1-7, deletion of SOP4 slows down export of wild-type Pma1p and Pma1-7 from the ER
RPS14B description Protein component of the small (40S) ribosomal subunit; required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; homologous to mammalian ribosomal protein S14 and bacterial S11; RPS14B has a paralog, RPS14A, that arose from the whole genome duplication
RPS22A description Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15A and bacterial S8; RPS22A has a paralog, RPS22B, that arose from the whole genome duplication
RPL39 description Ribosomal 60S subunit protein L39; required for ribosome biogenesis; loss of both Rpl31p and Rpl39p confers lethality; also exhibits genetic interactions with SIS1 and PAB1; homologous to mammalian ribosomal protein L39, no bacterial homolog
BUD19 description Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; 88% of ORF overlaps the verified gene RPL39; diploid mutant displays a weak budding pattern phenotype in a systematic assay
SWE1 description Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate
MNN5 description Alpha-1,2-mannosyltransferase; responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment
ATG36 description Pex3p interacting protein, required for pexophagy; interacts with Atg8p and Atg11p; mRNA is weakly cell cycle regulated, peaking in G2 phase; YJL185C is a non-essential gene
GON7 description Component of the EKC/KEOPS protein complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription; implicated in osmotic stress response; other complex members are Kae1p, Cgi121p, Pcc1p, and Bud32p
MNN11 description Subunit of a Golgi mannosyltransferase complex; this complex also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p
RBH1 description Putative protein of unknown function; expression is cell-cycle regulated as shown by microarray analysis; potential regulatory target of Mbp1p, which binds to the YJL181W promoter region; contains a PH-like domain; RBH1 has a paralog, RBH2, that arose from the whole genome duplication
ATP12 description Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase; conserved protein; required for assembly of alpha and beta subunits into F1 sector of mitochondrial F1F0 ATP synthase; human homolog ATPAF2 can complement yeast atp12 mutant; mutation of human homolog reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency
PFD1 description Subunit of heterohexameric prefoldin; prefoldin binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation
ATG27 description Type I membrane protein involved in autophagy and the Cvt pathway; may be involved in membrane delivery to the phagophore assembly site
RPL17B description Ribosomal 60S subunit protein L17B; required for processing of 27SB pre-rRNA and formation of stable 66S assembly intermediates; homologous to mammalian ribosomal protein L17 and bacterial L22; RPL17B has a paralog, RPL17A, that arose from the whole genome duplication
SWI3 description Subunit of the SWI/SNF chromatin remodeling complex; SWI/SNF regulates transcription by remodeling chromosomes; contains SANT domain that is required for SWI/SNF assembly; is essential for displacement of histone H2A-H2B dimers during ATP-dependent remodeling; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; relocates to the cytosol under hypoxic conditions
KRE9 description Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to severe growth defects, aberrant multibudded morphology, and mating defects
RFA3 description Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein complex involved in DNA replication, repair, recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication stress