Sign In

gene : TRM7

Sequence Viewer

Annotation Tags

ID gene326
Name WN66_00321
gene_biotype protein_coding
locus_tag WN66_00321
standard_name TRM7
Note YBR061C~TRM7~Verified
description 2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively; yeast null mutant can be functionally complemented by human FTSJ1, mutations in which have been implicated in nonsyndromic X-linked intellectual disability (NSXLID)
Dbxref SGD:S000000265
gbkey Gene

Location(s)

Start Position 371377
End Position 372309

Sequence: 933bp

Add 1kb Flanking
ATGGGTAAGA GCAGCAAAGA TAAAAGAGAT TTGTACTATA GAAAAGCAAA AGAGCAGGGC TATAGGGCTA GATCTGCTTT CAAACTACTT CAACTCAATG
ACCAATTTCA TTTCCTGGAT GATCCAAACT TAAAAAGAGT TGTAGATTTG TGTGCAGCAC CAGGTTCATG GTCACAAGTG CTCTCGAGAA AACTATTTGA
TGAAAGTCCC AGTTCAGATA AGGAGGACAG GAAAATTGTC TCTGTCGATT TACAACCGAT GTCCCCCATA CCTCATGTGA CAACGTTGCA AGCCGATATC
ACTCATCCTA AAACATTGGC GAGGATTCTA AAACTGTTTG GCAACGAAAA GGCCGATTTT GTTTGTAGTG ATGGTGCACC TGATGTTACT GGGCTACACG
ATCTTGACGA ATATGTGCAA CAACAGTTAA TTATGAGTGC GCTGCAACTT ACTGCATGCA TTCTGAAAAA AGGTGGAACT TTTGTGGCAA AGATCTTCAG
AGGTCGTGAT ATAGATATGC TATATTCCCA ATTGGGCTAT CTATTCGATA AAATCGTTTG CGCAAAGCCA AGATCATCAA GAGGTACATC TCTGGAAGCT
TTTATTGTTT GTTTAGGCTA TAACCCACCA TCCAATTGGA CACCAAAATT AGATGTAAAT ACATCCGTTG ATGAATTTTT TCAAGGCTGT TTTTTGAATA
AATTGTGTAT ATCAGACAAA TTGTCTCATT GGAATGAAGA GGAGAGAAAC ATAGCCGAAT TTATGGCTTG TGGAAGTCTT CAAAGTTTCG ACTCAGATGC
CACTTATCAT GACCTACCTT CTTCGGTTGC AGGCACTTCA TCGTCCTTAG ATCCTGTTCA AAGCCCGACG AACCCTCCCT ACAAGAAAGC TTTGGAATTA
AAAAGGAGCG GGAAACTCAC TAGATCAGTT TGA