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Label Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Type Attributes Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Start Pos Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558End Pos Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Strand Assembly Options
gene
[+]  WN66_07051 | gene3798 | WN66_07051 | protein_coding | Gene | potentially novel~GTK30K00100 | | | |
597 3446 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03748 | gene3799 | WN66_03748 | protein_coding | Gene | potentially novel~GTK30K00110 | | | |
3861 4676 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03749 | gene3800 | WN66_03749 | pseudogene | Gene | YKL225W~Dubious | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data | SGD:S000001708 | | true
5879 6234 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03750 | gene3801 | WN66_03750 | protein_coding | Gene | potentially novel~GTK30K00120 | | | |
7243 7605 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03751 | gene3802 | WN66_03751 | pseudogene | Gene | YKL223W~Dubious | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data | SGD:S000001706 | | true
7814 8150 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03752 | gene3803 | WN66_03752 | protein_coding | Gene | YKL222C~Verified | Protein of unknown function; may interact with ribosomes, based on co-purification experiments; similar to transcriptional regulators from the zinc cluster (binuclear cluster) family; null mutant is sensitive to caffeine | SGD:S000001705 | |
8934 11051 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
MCH2 gene
[+]  WN66_03753 | gene3804 | WN66_03753 | pseudogene | Gene | YKL221W~MCH2~Verified | Protein with similarity to mammalian monocarboxylate permeases; monocarboxylate permeases are involved in transport of monocarboxylic acids across the plasma membrane but mutant is not deficient in monocarboxylate transport | SGD:S000001704 | MCH2 | true
11538 12960 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
FRE2 gene
[+]  WN66_03754 | gene3805 | WN66_03754 | protein_coding | Gene | YKL220C~FRE2~Verified | Ferric reductase and cupric reductase; reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels | SGD:S000001703 | FRE2 |
14520 16655 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03755 | gene3806 | WN66_03755 | protein_coding | Gene | potentially novel~GTK30K00160 | | | |
19913 20782 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
SRY1 gene
[+]  WN66_03756 | gene3807 | WN66_03756 | protein_coding | Gene | YKL218C~SRY1~Verified | 3-hydroxyaspartate dehydratase; deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required in the presence of hydroxyaspartate; highly similar to mouse serine racemase (Srr) but has no serine racemase activity | SGD:S000001701 | SRY1 |
22717 23697 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
JEN1 gene
[+]  WN66_03757 | gene3808 | WN66_03757 | protein_coding | Gene | YKL217W~JEN1~Verified | Monocarboxylate/proton symporter of the plasma membrane; transport activity is dependent on the pH gradient across the membrane; mediates high-affinity uptake of carbon sources lactate, pyuvate, and acetate, and also of the micronutrient selenite, whose structure mimics that of monocarboxylates; expression and localization are tightly regulated, with transcription repression, mRNA degradation, and protein endocytosis and degradation all occurring in the presence of glucose | SGD:S000001700 | JEN1 |
27594 29444 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
URA1 gene
[+]  WN66_03758 | gene3809 | WN66_03758 | protein_coding | Gene | YKL216W~URA1~Verified | Dihydroorotate dehydrogenase; catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid | SGD:S000001699 | URA1 |
30562 31506 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
OXP1 gene
[+]  WN66_03759 | gene3810 | WN66_03759 | protein_coding | Gene | YKL215C~OXP1~Verified | 5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress | SGD:S000001698 | OXP1 |
32166 36026 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
YRA2 gene
[+]  WN66_03760 | gene3811 | WN66_03760 | protein_coding | Gene | YKL214C~YRA2~Verified | Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitute for the function of Yra1p in export of poly(A)+ mRNA from the nucleus | SGD:S000001697 | YRA2 |
36421 37032 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
DOA1 gene
[+]  WN66_03761 | gene3812 | WN66_03761 | protein_coding | Gene | YKL213C~DOA1,UFD3,ZZZ4~Verified | WD repeat protein required for ubiquitin-mediated protein degradation; ubiquitin binding cofactor that complexes with Cdc48p; required for ribophagy; controls cellular ubiquitin concentration; promotes efficient NHEJ in postdiauxic/stationary phase; facilitates N-terminus-dependent proteolysis of centromeric histone H3 (Cse4p) for faithful chromosome segregation; protein increases in abundance and relocalizes from nucleus to nuclear periphery upon DNA replication stress | SGD:S000001696 | DOA1 |
37299 39446 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
SAC1 gene
[+]  WN66_03762 | gene3813 | WN66_03762 | protein_coding | Gene | YKL212W~SAC1,RSD1~Verified | Phosphatidylinositol phosphate (PtdInsP) phosphatase; involved in hydrolysis of PtdIns[4]P in the early and medial Golgi; regulated by interaction with Vps74p; ER localized transmembrane protein which cycles through the Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis through the modulation of PtdIns(4)P metabolism | SGD:S000001695 | SAC1 |
39882 41753 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
TRP3 gene
[+]  WN66_03763 | gene3814 | WN66_03763 | protein_coding | Gene | YKL211C~TRP3~Verified | Indole-3-glycerol-phosphate synthase; forms bifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p | SGD:S000001694 | TRP3 |
42038 43492 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03764 | gene3815 | WN66_03764 | snoRNA | Gene | | | | |
44155 44255 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
UBA1 gene
[+]  WN66_03765 | gene3816 | WN66_03765 | protein_coding | Gene | YKL210W~UBA1~Verified | Ubiquitin activating enzyme (E1); involved in ubiquitin-mediated protein degradation and essential for viability; protein abundance increases in response to DNA replication stress | SGD:S000001693 | UBA1 |
44507 47581 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
STE6 gene
[+]  WN66_03766 | gene3817 | WN66_03766 | protein_coding | Gene | YKL209C~STE6~Verified | Plasma membrane ATP-binding cassette (ABC) transporter; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates multidrug resistance in many chemotherapy-resistant tumors by effluxing toxic compounds from the cell | SGD:S000001692 | STE6 |
47755 51627 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03767 | gene3818 | WN66_03767 | tRNA | Gene | tT(CGU)K | | | |
52066 52137 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
CBT1 gene
[+]  WN66_03768 | gene3819 | WN66_03768 | protein_coding | Gene | YKL208W~CBT1,SOC1~Verified | Protein involved in 5' RNA end processing; substrates include mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3' end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p | SGD:S000001691 | CBT1 |
52488 53303 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
EMC3 gene
[+]  WN66_03769 | gene3820 | WN66_03769 | protein_coding | Gene | YKL207W~AIM27,EMC3,LRC3~Verified | Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; required for respiratory growth; null mutant displays induction of the unfolded protein response; homologous to worm Y62E10A.10/EMC-3, fly CG6750, human TMEM111 | SGD:S000001690 | EMC3 |
53525 54286 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
ADD66 gene
[+]  WN66_03770 | gene3821 | WN66_03770 | protein_coding | Gene | YKL206C~ADD66,PBA2,POC2~Verified | Protein involved in 20S proteasome assembly; forms a heterodimer with Pba1p that binds to proteasome precursors; interaction with Pba1p-Add66p may affect function of the mature proteasome and its role in maintaining respiratory metabolism; similar to human PAC2 constituent of the PAC1-PAC2 complex involved in proteasome assembly | SGD:S000001689 | ADD66 |
54337 55140 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
LOS1 gene
[+]  WN66_03771 | gene3822 | WN66_03771 | protein_coding | Gene | YKL205W~LOS1~Verified | Nuclear pore protein; involved in nuclear export of pre-tRNA and in re-export of mature tRNAs after their retrograde import from the cytoplasm; deletion mutation extends replicative lifespan, as does exclusion of Los1p from the nucleus in response to caloric restriction | SGD:S000001688 | LOS1 |
55382 58684 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
EAP1 gene
[+]  WN66_03772 | gene3823 | WN66_03772 | protein_coding | Gene | YKL204W~EAP1~Verified | eIF4E-associated protein, competes with eIF4G for binding to eIF4E; accelerates mRNA degradation by promoting decapping, facilitated by interaction with eIF4E; essential for Puf5p mediated repression; associates with Puf5p and Dhh1p; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade | SGD:S000001687 | EAP1 |
59035 60933 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
TOR2 gene
[+]  WN66_03773 | gene3824 | WN66_03773 | protein_coding | Gene | YKL203C~TOR2,DRR2~Verified | PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis; TOR2 has a paralog, TOR1, that arose from the whole genome duplication | SGD:S000001686 | TOR2 |
61266 68690 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03774 | gene3825 | WN66_03774 | protein_coding | Gene | YKL202W~Dubious | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data | SGD:S000001685 | |
69152 69733 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
MNN4 gene
[+]  WN66_03775 | gene3826 | WN66_03775 | protein_coding | Gene | YKL201C~MNN4,YKL200C~Verified | Putative positive regulator of mannosylphosphate transferase Mnn6p; involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases; coding sequence contains length polymorphisms in different strains; MNN4 has a paralog, YJR061W, that arose from the whole genome duplication | SGD:S000001684 | MNN4 |
69261 72800 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
PTK1 gene
[+]  WN66_03776 | gene3827 | WN66_03776 | protein_coding | Gene | YKL198C~PTK1,KKT8,POT1,STK1,YKL199C,YKT9~Verified | Putative serine/threonine protein kinase; regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein; PTK1 has a paralog, PTK2, that arose from the whole genome duplication | SGD:S000001681 | PTK1 |
73566 75548 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
PEX1 gene
[+]  WN66_03777 | gene3828 | WN66_03777 | protein_coding | Gene | YKL197C~PEX1,PAS1~Verified | AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis; mutations in human PEX1 can lead to severe peroxisomal disorders and early death | SGD:S000001680 | PEX1 |
76062 79193 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03778 | gene3829 | WN66_03778 | tRNA | Gene | tN(GUU)K | | | |
79953 80026 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
YKT6 gene
[+]  WN66_03779 | gene3830 | WN66_03779 | protein_coding | Gene | YKL196C~YKT6~Verified | Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus; human homolog YKT6 can complement yeast ykt6 mutant | SGD:S000001679 | YKT6 |
80267 80869 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
MIA40 gene
[+]  WN66_03780 | gene3831 | WN66_03780 | protein_coding | Gene | YKL195W~MIA40,FMP15,TIM40~Verified | Import and assembly protein in mitochondrial intermembrane space; component of MIA pathway which mediates import and oxidative folding of substrates including small proteins containing twin cysteine motifs; acts in concert with Erv1p, which oxidizes the cysteine residues of Mia40p to comprise a disulfide relay system that catalyzes import; also mediates folding of Atp23p via a chaperone-like activity; forms a dimer that binds iron-sulfur cluster in vitro | SGD:S000001678 | MIA40 |
81156 82367 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
MST1 gene
[+]  WN66_03781 | gene3832 | WN66_03781 | protein_coding | Gene | YKL194C~MST1~Verified | Mitochondrial threonyl-tRNA synthetase; aminoacylates both the canonical threonine tRNA tT(UGU)Q1 and the unusual threonine tRNA tT(UAG)Q2 in vitro; lacks a typical editing domain, but has pre-transfer editing activity stimulated by the unusual tRNA-Thr | SGD:S000001677 | MST1 |
82593 83981 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
SDS22 gene
[+]  WN66_03782 | gene3833 | WN66_03782 | protein_coding | Gene | YKL193C~SDS22,EGP1~Verified | Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p; whether it functions as a positive or negative regulator of Glc7p is controversial; involved in the regulation of Glc7p nuclear localization and function | SGD:S000001676 | SDS22 |
84214 85230 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
ACP1 gene
[+]  WN66_03783 | gene3834 | WN66_03783 | protein_coding | Gene | YKL192C~ACP1~Verified | Mitochondrial matrix acyl carrier protein; involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p | SGD:S000001675 | ACP1 |
85508 85885 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
DPH2 gene
[+]  WN66_03784 | gene3835 | WN66_03784 | protein_coding | Gene | YKL191W~DPH2~Verified | Protein required for synthesis of diphthamide; required along with Dph1p, Kti11p, Jjj3p, and Dph5p; diphthamide is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p | SGD:S000001674 | DPH2 |
86383 87987 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
CNB1 gene
[+]  WN66_03785 | gene3836 | WN66_03785 | protein_coding | Gene | YKL190W~CNB1,CRV1,YCN2~Verified | Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress | SGD:S000001673 | CNB1 |
88295 88898 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03786 | gene3837 | WN66_03786 | tRNA | Gene | tL(UAA)K | | | |
89558 89641 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
HYM1 gene
[+]  WN66_03787 | gene3838 | WN66_03787 | protein_coding | Gene | YKL189W~HYM1~Verified | Component of the RAM signaling network; is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response | SGD:S000001672 | HYM1 |
90051 91250 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
PXA2 gene
[+]  WN66_03788 | gene3839 | WN66_03788 | protein_coding | Gene | YKL188C~PXA2,PAT1~Verified | Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p; required for import of long-chain fatty acids into peroxisomes; similar to human adrenoleukodystrophy transportesr ABCD1 and ABCD2, and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; human ABCD1 and ABCD2 can each partially complement yeast pxa1 pxa2 double null mutant | SGD:S000001671 | PXA2 |
91572 94133 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
FAT3 gene
[+]  WN66_03789 | gene3840 | WN66_03789 | protein_coding | Gene | YKL187C~Verified | Protein required for fatty acid uptake; protein abundance increases in cortical patches in response to oleate exposure; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; FAT3 has a paralog, YLR413W, that arose from the whole genome duplication | SGD:S000001670 | FAT3 |
94635 96887 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
MTR2 gene
[+]  WN66_03790 | gene3841 | WN66_03790 | protein_coding | Gene | YKL186C~MTR2~Verified | mRNA transport regulator; essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA | SGD:S000001669 | MTR2 |
98099 98653 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
ASH1 gene
[+]  WN66_03791 | gene3842 | WN66_03791 | protein_coding | Gene | YKL185W~ASH1~Verified | Component of the Rpd3L histone deacetylase complex; zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate | SGD:S000001668 | ASH1 |
99854 101620 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
SPE1 gene
[+]  WN66_03792 | gene3843 | WN66_03792 | protein_coding | Gene | YKL184W~SPE1,ORD1,SPE10~Verified | Ornithine decarboxylase; catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines; deletion decreases lifespan, and increases necrotic cell death and ROS generation | SGD:S000001667 | SPE1 |
102113 103513 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_03793 | gene3844 | WN66_03793 | protein_coding | Gene | YKL183C-A~Uncharacterized | Putative protein of unknown function; identified by fungal homology and RT-PCR | SGD:S000028558 | |
103750 103962 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
LOT5 gene
[+]  WN66_03794 | gene3845 | WN66_03794 | protein_coding | Gene | YKL183W~LOT5~Verified | Protein of unknown function; gene expression increases in cultures shifted to a lower temperature; protein abundance increases in response to DNA replication stress | SGD:S000001666 | LOT5 |
104076 104996 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
FAS1 gene
[+]  WN66_03795 | gene3846 | WN66_03795 | protein_coding | Gene | YKL182W~FAS1~Verified | Beta subunit of fatty acid synthetase; complex catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities | SGD:S000001665 | FAS1 |
106027 112182 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
PRS1 gene
[+]  WN66_03796 | gene3847 | WN66_03796 | protein_coding | Gene | YKL181W~PRS1,PRP1~Verified | 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; plays a key role in cell wall integrity (CWI) pathway; one of five related enzymes, which are active as heteromultimeric complexes; missense mutations in human homolog PRPS1 are associated with neuropathic Arts syndrome and Charcot-Marie Tooth (CMTX5) disease | SGD:S000001664 | PRS1 |
112672 113955 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence