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Label Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Type Attributes Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Start Pos Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558End Pos Sort off f637db7715914123844374c755c2460a7dfbccf7ada7dd2f49b33af0389a6558Strand Assembly Options
gene
[+]  WN66_04668 | gene4750 | WN66_04668 | protein_coding | Gene | YML132W~Verified | | | |
2011 3156 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04669 | gene4751 | WN66_04669 | protein_coding | Gene | YML131W~Verified | Protein of unknown function; similar to medium chain dehydrogenase/reductases; expression induced by stresses including osmotic shock, DNA damaging agents, and other chemicals; GFP-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress | SGD:S000004600 | |
4970 6067 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
ERO1 gene
[+]  WN66_04670 | gene4752 | WN66_04670 | protein_coding | Gene | YML130C~ERO1~Verified | Thiol oxidase required for oxidative protein folding in the ER; essential for maintaining ER redox balance; feedback regulated via reduction and oxidation of regulatory bonds; reduced Pdi1p activates Ero1p by direct reduction of Ero1p regulatory bonds; depletion of thiol substrates and accumulation of oxidized Pdi1p results in inactivation of Ero1p by both Pdi1p-mediated oxidation and autonomous oxidation of Ero1p regulatory bonds; ero1-1 mutation complemented by human ERO1L | SGD:S000004599 | ERO1 |
6255 7946 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
COX14 gene
[+]  WN66_04671 | gene4753 | WN66_04671 | protein_coding | Gene | YML129C~COX14~Verified | Mitochondrial cytochrome c oxidase (complex IV) assembly factor; also involved in translational regulation of Cox1p and prevention of Cox1p aggregation before assembly; associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; located in the mitochondrial membrane | SGD:S000004598 | COX14 |
9314 9526 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04672 | gene4754 | WN66_04672 | protein_coding | Gene | potentially novel~GTK30M00140 | | | |
9441 9722 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
MSC1 gene
[+]  WN66_04673 | gene4755 | WN66_04673 | protein_coding | Gene | YML128C~MSC1~Verified | Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated | SGD:S000004597 | MSC1 |
9909 11450 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
RSC9 gene
[+]  WN66_04674 | gene4756 | WN66_04674 | protein_coding | Gene | YML127W~RSC9~Verified | Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway | SGD:S000004596 | RSC9 |
11838 13583 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
ERG13 gene
[+]  WN66_04675 | gene4757 | WN66_04675 | protein_coding | Gene | YML126C~ERG13,HMGS~Verified | 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase; catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis | SGD:S000004595 | ERG13 |
13834 15309 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
PGA3 gene
[+]  WN66_04676 | gene4758 | WN66_04676 | protein_coding | Gene | YML125C~PGA3,NQR1~Verified | Putative cytochrome b5 reductase, localized to the plasma membrane; may be involved in regulation of lifespan; required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking; PGA3 has a paralog, AIM33, that arose from the whole genome duplication | SGD:S000004594 | PGA3 |
15535 16473 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
TUB3 gene
[+]  WN66_04677 | gene4759 | WN66_04677 | protein_coding | Gene | YML124C~TUB3~Verified | Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p; TUB3 has a paralog, TUB1, that arose from the whole genome duplication | SGD:S000004593 | TUB3 |
16809 18444 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
PHO84 gene
[+]  WN66_04678 | gene4760 | WN66_04678 | protein_coding | Gene | YML123C~PHO84,phoT~Verified | High-affinity inorganic phosphate (Pi) transporter; also low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p; cells overexpressing Pho84p accumulate heavy metals but do not develop symptoms of metal toxicity | SGD:S000004592 | PHO84 |
18800 20563 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04679 | gene4761 | WN66_04679 | protein_coding | Gene | YML122C~Dubious | Putative protein of unknown function; conserved among S. cerevisiae strains; YML122C is not an essential gene | SGD:S000004591 | |
20801 21181 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
GTR1 gene
[+]  WN66_04680 | gene4762 | WN66_04680 | protein_coding | Gene | YML121W~GTR1~Verified | Subunit of a TORC1-stimulating GTPase complex; subunit of the heterodimeric Gtr1-Gtr2 GTPase complex that stimulates TORC1 in response to amino acid stimulation; tethered to the vacuolar membrane as part of the EGOC, a complex required for sorting of Gap1p and microautophagy; involved in phosphate transport and telomeric chromatin silencing; activated by the the Iml1p (GAP) subunit of the SEACIT complex; similar to human RagA and RagB | SGD:S000004590 | GTR1 |
21687 22619 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
NDI1 gene
[+]  WN66_04681 | gene4763 | WN66_04681 | protein_coding | Gene | YML120C~NDI1~Verified | NADH:ubiquinone oxidoreductase; transfers electrons from NADH to ubiquinone in respiratory chain but does not pump protons, in contrast to higher eukaryotic multisubunit respiratory complex I; upon apoptotic stress, is activated in mitochondria by N-terminal cleavage, then translocates to cytoplasm to induce apoptosis; homolog of human AIFM2; yeast NDI1 complements several phenotypes of human cell line with mutated MT-ND4, implicated in Leber hereditary optic neuropathy | SGD:S000004589 | NDI1 |
23020 24561 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04682 | gene4764 | WN66_04682 | protein_coding | Gene | YML119W~Uncharacterized | Putative protein of unknown function; YML119W is not an essential gene; potential Cdc28p substrate | SGD:S000004588 | |
25365 26438 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
NGL3 gene
[+]  WN66_04683 | gene4765 | WN66_04683 | protein_coding | Gene | YML118W~NGL3~Verified | 3'-5' exonuclease specific for poly-A RNAs; has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p; NGL3 has a paralog, NGL2, that arose from the whole genome duplication | SGD:S000004587 | NGL3 |
27088 28596 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
NAB6 gene
[+]  WN66_04684 | gene4766 | WN66_04684 | protein_coding | Gene | YML117W~NAB6~Verified | Putative RNA-binding protein; associates with mRNAs encoding cell wall proteins in high-throughput studies; deletion mutants display increased sensitivity to some cell wall disrupting agents; expression negatively regulated by cAMP | SGD:S000004585 | NAB6 |
28997 32401 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
ATR1 gene
[+]  WN66_04685 | gene4767 | WN66_04685 | protein_coding | Gene | YML116W~ATR1,SNQ1~Verified | Multidrug efflux pump of the major facilitator superfamily; required for resistance to aminotriazole and 4-nitroquinoline-N-oxide; ATR1 has a paralog, YMR279C, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress | SGD:S000004584 | ATR1 |
32951 34579 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
VAN1 gene
[+]  WN66_04686 | gene4768 | WN66_04686 | protein_coding | Gene | YML115C~VAN1,LDB13,VRG7,VRG8~Verified | Component of the mannan polymerase I; complex contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant | SGD:S000004583 | VAN1 |
34941 36548 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
TAF8 gene
[+]  WN66_04687 | gene4769 | WN66_04687 | protein_coding | Gene | YML114C~TAF8,TAF65~Verified | TFIID subunit (65 kDa); involved in RNA polymerase II transcription initiation | SGD:S000004582 | TAF8 |
36797 38329 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04688 | gene4770 | WN66_04688 | protein_coding | Gene | YML113W~Verified | | | |
38799 39536 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
CTK3 gene
[+]  WN66_04689 | gene4771 | WN66_04689 | protein_coding | Gene | YML112W~CTK3~Verified | Gamma subunit of C-terminal domain kinase I; CTDK-I phosphorylates RNA polymerase II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and also phosphorylates ribosomal protein Rps2p to increase translational fidelity; protein abundance increases in response to DNA replication stress | SGD:S000004580 | CTK3 |
39808 40698 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
BUL2 gene
[+]  WN66_04690 | gene4772 | WN66_04690 | protein_coding | Gene | YML111W~BUL2~Verified | Component of the Rsp5p E3-ubiquitin ligase complex; involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions; BUL2 has a paralog, BUL1, that arose from the whole genome duplication | SGD:S000004579 | BUL2 |
41693 44455 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
COQ5 gene
[+]  WN66_04691 | gene4773 | WN66_04691 | protein_coding | Gene | YML110C~COQ5,DBI56~Verified | 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase; involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes; respiratory defect of the null mutant is partially complemented by human COQ5 | SGD:S000004578 | COQ5 |
44785 45708 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
ZDS2 gene
[+]  WN66_04692 | gene4774 | WN66_04692 | protein_coding | Gene | YML109W~ZDS2,CES4~Verified | Protein with a role in regulating Swe1p-dependent polarized growth; involved in maintenance of Cdc55p in the cytoplasm where it promotes mitotic entry; interacts with silencing proteins at the telomere; implicated in the mitotic exit network through regulation of Cdc14p localization; ZDS2 has a paralog, ZDS1, that arose from the whole genome duplication | SGD:S000004577 | ZDS2 |
46394 49225 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04693 | gene4775 | WN66_04693 | protein_coding | Gene | YML108W~Verified | Protein of unknown function; structure defines a new subfamily of the split beta-alpha-beta sandwiches; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YML108W is not an essential gene; relative distribution to the nucleus increases upon DNA replication stress | SGD:S000004576 | |
49551 49868 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
PML39 gene
[+]  WN66_04694 | gene4776 | WN66_04694 | protein_coding | Gene | YML107C~PML39~Verified | Protein required for nuclear retention of unspliced pre-mRNAs; required along with Mlp1p and Pml1p; anchored to nuclear pore complex via Mlp1p and Mlp2p; found with the subset of nuclear pores farthest from the nucleolus; may interact with ribosomes | SGD:S000004575 | PML39 |
50023 51027 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
URA5 gene
[+]  WN66_04695 | gene4777 | WN66_04695 | protein_coding | Gene | YML106W~URA5,PYR5~Verified | Major orotate phosphoribosyltransferase (OPRTase) isozyme; catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; URA5 has a paralog, URA10, that arose from the whole genome duplication | SGD:S000004574 | URA5 |
51531 52211 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
SEC65 gene
[+]  WN66_04696 | gene4778 | WN66_04696 | protein_coding | Gene | YML105C~SEC65~Verified | Subunit of the signal recognition particle (SRP); involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19 | SGD:S000004573 | SEC65 |
52624 53445 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
MDM1 gene
[+]  WN66_04697 | gene4779 | WN66_04697 | protein_coding | Gene | YML104C~MDM1~Verified | PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs; anchored in the ER membrane at nucleus-vacuole junctions and binds phosphatidylinositol 3-phosphate (PtdIns-3-P) in the vacuolar membrane via its Phox homology (PX) domain; expressed predominantly in late G1 to early S phase of the cell cycle; mutation affects nuclear and mitochondrial transmission to daughter buds; similar to 4 human genes, one of which (SNX14) is associated with neurological disease | SGD:S000004572 | MDM1 |
53696 57079 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
NUP188 gene
[+]  WN66_04698 | gene4780 | WN66_04698 | protein_coding | Gene | YML103C~NUP188~Verified | Subunit of the inner ring of the nuclear pore complex (NPC); contributes to NPC organization and nucleocytoplasmic transport; homologous to human NUP188 | SGD:S000004571 | NUP188 |
57340 62301 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04699 | gene4781 | WN66_04699 | snoRNA | Gene | | | | |
62520 62690 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
CAC2 gene
[+]  WN66_04700 | gene4782 | WN66_04700 | protein_coding | Gene | YML102W~CAC2~Verified | Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p; chromatin assembly by CAF-1 is important for multiple processes including silencing at telomeres, mating type loci, and rDNA; maintenance of kinetochore structure, deactivation of the DNA damage checkpoint after DNA repair, chromatin dynamics during transcription; and repression of divergent transcription; relocalizes to the cytosol in response to hypoxia | SGD:S000004570 | CAC2 |
63046 64452 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04701 | gene4783 | WN66_04701 | protein_coding | Gene | YML101C-A~YML102C-A~Dubious | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data | SGD:S000004569 | |
64161 64478 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
CUE4 gene
[+]  WN66_04702 | gene4784 | WN66_04702 | protein_coding | Gene | YML101C~CUE4~Verified | Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; CUE4 has a paralog, CUE1, that arose from the whole genome duplication | SGD:S000004568 | CUE4 |
64487 64840 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04703 | gene4785 | WN66_04703 | protein_coding | Gene | YML100W-A~Uncharacterized | Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching | SGD:S000028688 | |
64890 65102 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
TSL1 gene
[+]  WN66_04704 | gene4786 | WN66_04704 | protein_coding | Gene | YML100W~TSL1~Verified | Large subunit of trehalose 6-phosphate synthase/phosphatase complex; Tps1p-Tps2p complex converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose; contributes to survival to acute lethal heat stress; mutant has aneuploidy tolerance; protein abundance increases in response to DNA replication stress; TSL1 has a paralog, TPS3, that arose from the whole genome duplication | SGD:S000004566 | TSL1 |
65377 68673 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04705 | gene4787 | WN66_04705 | pseudogene | Gene | YML099W-A~YML100W-A~Dubious | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF ARG81/YML099C | SGD:S000004567 | | true
68982 69311 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
ARG81 gene
[+]  WN66_04706 | gene4788 | WN66_04706 | protein_coding | Gene | YML099C~ARG81,ARGR2,ARGRII~Verified | Zinc finger transcription factor involved in arginine-responsive genes; Zn(2)-Cys(6) binuclear cluster domain type; involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p | SGD:S000004565 | ARG81 |
69151 71793 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
TAF13 gene
[+]  WN66_04707 | gene4789 | WN66_04707 | protein_coding | Gene | YML098W~TAF13,FUN81,TAF19~Verified | TFIID subunit (19 kDa); involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors | SGD:S000004564 | TAF13 |
72021 72524 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
VPS9 gene
[+]  WN66_04708 | gene4790 | WN66_04708 | protein_coding | Gene | YML097C~VPS9,VPL31,VPT9~Verified | Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a VPS9 domain; binds ubiquitin | SGD:S000004563 | VPS9 |
73087 74442 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04709 | gene4791 | WN66_04709 | protein_coding | Gene | YML096W~Uncharacterized | Putative protein with similarity to asparagine synthetases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YML096W is not an essential gene and partially overlaps the verified gene RAD10 | SGD:S000004562 | |
74661 76238 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
RAD10 gene
[+]  WN66_04710 | gene4792 | WN66_04710 | protein_coding | Gene | YML095C~RAD10~Verified | Single-stranded DNA endonuclease (with Rad1p); cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein | SGD:S000004560 | RAD10 |
76233 76865 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04711 | gene4793 | WN66_04711 | protein_coding | Gene | YML094C-A~YML095C-A~Dubious | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene GIM5/YML094W; deletion confers sensitivity to GSAO | SGD:S000004561 | |
76971 77372 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
GIM5 gene
[+]  WN66_04712 | gene4794 | WN66_04712 | protein_coding | Gene | YML094W~GIM5,PFD5~Verified | Subunit of the heterohexameric cochaperone prefoldin complex; prefoldin binds specifically to cytosolic chaperonin and transfers target proteins to it; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation | SGD:S000004559 | GIM5 |
77027 77601 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
UTP14 gene
[+]  WN66_04713 | gene4795 | WN66_04713 | protein_coding | Gene | YML093W~UTP14~Verified | Subunit of U3-containing Small Subunit (SSU) processome complex; involved in production of 18S rRNA and assembly of small ribosomal subunit | SGD:S000004558 | UTP14 |
77842 80541 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
PRE8 gene
[+]  WN66_04714 | gene4796 | WN66_04714 | protein_coding | Gene | YML092C~PRE8~Verified | Alpha 2 subunit of the 20S proteasome | SGD:S000004557 | PRE8 |
80739 81491 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
RPM2 gene
[+]  WN66_04715 | gene4797 | WN66_04715 | protein_coding | Gene | YML091C~RPM2~Verified | Protein subunit of mitochondrial RNase P; has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus | SGD:S000004556 | RPM2 |
81800 85408 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04716 | gene4798 | WN66_04716 | protein_coding | Gene | YML090W~Dubious | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YML089C; exhibits growth defect on a non-fermentable (respiratory) carbon source | SGD:S000004555 | |
85421 85807 F GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence
gene
[+]  WN66_04717 | gene4799 | WN66_04717 | protein_coding | Gene | YML089C~Dubious | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage | SGD:S000004554 | |
85718 86086 R GLBRC Y22-3 ( GCA_001634645.1 ) Details | Sequence