Feature Listing

[+]  CRG71 | gene3381 | CRG71 | protein_coding | Gene | potentially novel~GTK30J00190 | | | | | WN66_03336

[-]

[+]  | gene793 | WN66_00784 | pseudogene | Gene | potentially novel~GTK30D00170 | | | | true | WN66_00784

[-]

[+]  | gene5291 | WN66_05207 | protein_coding | Gene | YNL327W~EGT2~Verified | SGD:S000005271 | Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner | EGT2 | | WN66_05207

[-]

[+]  | gene6347 | WN66_06258 | protein_coding | Gene | YPL271W~ATP15,ATPEPSILON~Verified | SGD:S000006192 | Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase; which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated | ATP15 | | WN66_06258

[-]

[+]  SUC72 | gene3114 | SUC72 | protein_coding | Gene | potentially novel~GTK30I00160 | | | | | WN66_03071

[-]

[+]  | gene603 | WN66_00597 | protein_coding | Gene | YCL063W~VAC17,YCL062W~Verified | SGD:S000000568 | Phosphoprotein involved in vacuole inheritance; degraded in late M phase of the cell cycle; acts as a vacuole-specific receptor for myosin Myo2p; involved in regulation of asymmetric inheritance of aggregated/misfolded proteins and age reset | VAC17 | | WN66_00597

[-]

[+]  | gene6882 | WN66_06868 | misc_RNA | Gene | | | | | | WN66_06868

[-]

[+]  | gene9 | WN66_00010 | protein_coding | Gene | YAL062W~GDH3,FUN51~Verified | SGD:S000000058 | NADP(+)-dependent glutamate dehydrogenase; synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; GDH3 has a paralog, GDH1, that arose from the whole genome duplication | GDH3 | | WN66_00010

[-]

[+]  | gene2006 | WN66_01980 | protein_coding | Gene | YFL057C~AAD16 | SGD:S000001837 | | | | WN66_01980

[-]

[+]  | gene6348 | WN66_06259 | protein_coding | Gene | YPL270W~MDL2~Verified | SGD:S000006191 | Mitochondrial inner membrane half-type ABC transporter; required for respiratory growth at high temperature; localizes to vacuole membrane in response to H2O2; similar to human TAP1 and TAP2 implicated in bare lymphocyte syndrome and Wegener-like granulomatosis | MDL2 | | WN66_06259

[-]

[+]  | gene5735 | WN66_05647 | protein_coding | Gene | YOL155C~HPF1~Verified | SGD:S000005515 | Haze-protective mannoprotein; reduces the particle size of aggregated proteins in white wines | HPF1 | | WN66_05647

[-]

[+]  | gene6928 | WN66_06780 | protein_coding | Gene | Q0075~AI5_BETA~Uncharacterized | | | | | WN66_06780

[-]

[+]  | gene794 | WN66_00785 | protein_coding | Gene | YDL245C~HXT15~Verified | SGD:S000002404 | Putative transmembrane polyol transporter; supports growth on and uptake of mannitol, sorbitol and xylitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; similarity to hexose transporters; expression is induced by low levels of glucose and repressed by high levels of glucose | HXT15 | | WN66_00785

[-]

[+]  | gene2007 | WN66_01981 | protein_coding | Gene | YFL056C~AAD6 | SGD:S000001838 | Putative aryl-alcohol dehydrogenase; involved in oxidative stress response; similar to P. chrysosporium aryl-alcohol dehydrogenase; ORFs AAD6/YFL056C and AAD16/YFL057C are displaced from one another by -1 frameshift; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family; expression induced in cells treated with the mycotoxin patulin | AAD6 | | WN66_01981

[-]

[+]  | gene4760 | WN66_04678 | protein_coding | Gene | YML123C~PHO84,phoT~Verified | SGD:S000004592 | High-affinity inorganic phosphate (Pi) transporter; also low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p; cells overexpressing Pho84p accumulate heavy metals but do not develop symptoms of metal toxicity | PHO84 | | WN66_04678

[-]

[+]  | gene4175 | WN66_04119 | protein_coding | Gene | YLL055W~YCT1~Verified | SGD:S000003978 | High-affinity cysteine-specific transporter; has similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene | YCT1 | | WN66_04119

[-]

[+]  | gene2796 | WN66_02755 | protein_coding | Gene | YHL038C~CBP2~Verified | SGD:S000001030 | Required for splicing of the group I intron bI5 of the COB pre-mRNA; nuclear-encoded mitochondrial protein that binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene | CBP2 | | WN66_02755

[-]

[+]  | gene604 | WN66_00598 | protein_coding | Gene | YCL061C~MRC1,YCL060C~Verified | SGD:S000000566 | S-phase checkpoint protein required for DNA replication; couples DNA helicase and polymerase; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; defines a novel S-phase checkpoint with Hog1p that coordinates DNA replication and transcription upon osmostress; protects uncapped telomeres; Dia2p-dependent degradation mediates checkpoint recovery; mammalian claspin homolog | MRC1 | | WN66_00598

[-]

[+]  | gene130 | WN66_00130 | protein_coding | Gene | potentially novel~GTK30B00160 | | | | | WN66_00130

[-]

[+]  | gene3806 | WN66_03755 | protein_coding | Gene | potentially novel~GTK30K00160 | | | | | WN66_03755

[-]

[+]  | gene10 | WN66_00011 | protein_coding | Gene | YAL061W~BDH2~Uncharacterized | SGD:S000000057 | Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3 | BDH2 | | WN66_00011

[-]

[+]  | gene1665 | WN66_01643 | protein_coding | Gene | YEL070W~Uncharacterized | | | | | WN66_01643

[-]

[+]  THI75 | gene3382 | THI75 | protein_coding | Gene | potentially novel~GTK30J00200 | | | | | WN66_03337

[-]

[+]  | gene4761 | WN66_04679 | protein_coding | Gene | YML122C~Dubious | SGD:S000004591 | Putative protein of unknown function; conserved among S. cerevisiae strains; YML122C is not an essential gene | | | WN66_04679

[-]

[+]  | gene6349 | WN66_06260 | protein_coding | Gene | YPL269W~KAR9~Verified | SGD:S000006190 | Spindle positioning factor; orients astral microtubules, connecting them to actin cables at the cortex with Bim1p and Myo2, resulting in proper spindle positioning; targeted for StuBL-dependent degradation at kinetochores by Slx5p-Slx8p, ensuring chromosome transmission fidelity and correct spindle positioning; role in karyogamy; localizes to the shmoo tip, the growing bud-tip, the nucleus, the kinetochore, the spindle and microtubules; homolog of adenomatous polyposis coli | KAR9 | | WN66_06260

[-]

[+]  | gene2008 | WN66_01982 | protein_coding | Gene | YFL055W~AGP3~Verified | SGD:S000001839 | Low-affinity amino acid permease; may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition | AGP3 | | WN66_01982

[-]

[+]  | gene5292 | WN66_05208 | protein_coding | Gene | YNL326C~PFA3~Verified | SGD:S000005270 | Palmitoyltransferase for Vac8p; required for vacuolar membrane fusion; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; autoacylates; required for vacuolar integrity under stress conditions | PFA3 | | WN66_05208

[-]

[+]  | gene2797 | WN66_02756 | protein_coding | Gene | YHL037C~Dubious | SGD:S000001029 | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data | | | WN66_02756

[-]

[+]  | gene4762 | WN66_04680 | protein_coding | Gene | YML121W~GTR1~Verified | SGD:S000004590 | Subunit of a TORC1-stimulating GTPase complex; subunit of the heterodimeric Gtr1-Gtr2 GTPase complex that stimulates TORC1 in response to amino acid stimulation; tethered to the vacuolar membrane as part of the EGOC, a complex required for sorting of Gap1p and microautophagy; involved in phosphate transport and telomeric chromatin silencing; activated by the the Iml1p (GAP) subunit of the SEACIT complex; similar to human RagA and RagB | GTR1 | | WN66_04680

[-]

[+]  | gene11 | WN66_00012 | protein_coding | Gene | YAL060W~BDH1,BDH~Verified | SGD:S000000056 | NAD-dependent (R,R)-butanediol dehydrogenase; catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source | BDH1 | | WN66_00012

[-]

[+]  | gene131 | WN66_00131 | protein_coding | Gene | YBL108C-A~Verified | | | | | WN66_00131

[-]

[+]  | gene2798 | WN66_02757 | protein_coding | Gene | YHL036W~MUP3~Verified | SGD:S000001028 | Low affinity methionine permease; similar to Mup1p | MUP3 | | WN66_02757

[-]

[+]  | gene6929 | WN66_06781 | protein_coding | Gene | ATP8|Q0080 | | | | | WN66_06781

[-]

[+]  | gene4176 | WN66_04120 | protein_coding | Gene | YLL054C~Uncharacterized | SGD:S000003977 | Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene | | | WN66_04120

[-]

[+]  | gene132 | WN66_00132 | pseudogene | Gene | YBL108W~Dubious | SGD:S000000204 | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data | | true | WN66_00132

[-]

[+]  | gene5293 | WN66_05209 | protein_coding | Gene | YNL325C~FIG4~Verified | SGD:S000005269 | Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase; required for efficient mating and response to osmotic shock; physically associates with and regulated by Vac14p; contains a SAC1-like domain; homologous to human FIG4, which is associated with CMT4J, a form of Charcot-Marie-Tooth disorder | FIG4 | | WN66_05209

[-]

[+]  | gene3807 | WN66_03756 | protein_coding | Gene | YKL218C~SRY1~Verified | SGD:S000001701 | 3-hydroxyaspartate dehydratase; deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required in the presence of hydroxyaspartate; highly similar to mouse serine racemase (Srr) but has no serine racemase activity | SRY1 | | WN66_03756

[-]

[+]  | gene6930 | WN66_06782 | protein_coding | Gene | ATP6|Q0085 | | | | | WN66_06782

[-]

[+]  | gene795 | WN66_00786 | protein_coding | Gene | YDL244W~THI13~Verified | SGD:S000002403 | Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP | THI13 | | WN66_00786

[-]

[+]  | gene4763 | WN66_04681 | protein_coding | Gene | YML120C~NDI1~Verified | SGD:S000004589 | NADH:ubiquinone oxidoreductase; transfers electrons from NADH to ubiquinone in respiratory chain but does not pump protons, in contrast to higher eukaryotic multisubunit respiratory complex I; upon apoptotic stress, is activated in mitochondria by N-terminal cleavage, then translocates to cytoplasm to induce apoptosis; homolog of human AIFM2; yeast NDI1 complements several phenotypes of human cell line with mutated MT-ND4, implicated in Leber hereditary optic neuropathy | NDI1 | | WN66_04681

[-]

[+]  | gene1666 | WN66_01644 | pseudogene | Gene | YEL068C~Uncharacterized | SGD:S000000794 | Protein of unknown function; expressed at both mRNA and protein levels; SWAT-GFP and seamless-GFP fusion proteins localize to the endoplasmic reticulum and mCherry fusion protein localizes to the vacuole | | true | WN66_01644

[-]

[+]  | gene3115 | WN66_03072 | protein_coding | Gene | potentially novel~GTK30I00170 | | | | | WN66_03072

[-]

[+]  | gene6350 | WN66_06261 | protein_coding | Gene | YPL268W~PLC1~Verified | SGD:S000006189 | Phospholipase C; hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes; Plc1p and inositol polyphosphates are required for acetyl-CoA homeostasis which regulates global histone acetylation | PLC1 | | WN66_06261

[-]

[+]  | gene12 | WN66_00013 | protein_coding | Gene | YAL059C-A~Dubious | SGD:S000028734 | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified gene ECM1/YAL059W | | | WN66_00013

[-]

[+]  | gene13 | WN66_00014 | pseudogene | Gene | YAL059W~ECM1~Verified | SGD:S000000055 | Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm | ECM1 | true | WN66_00014

[-]

[+]  | gene2161 | WN66_02130 | protein_coding | Gene | YGL255W~ZRT1~Verified | SGD:S000003224 | High-affinity zinc transporter of the plasma membrane; responsible for the majority of zinc uptake; transcription is induced under low-zinc conditions by the Zap1p transcription factor | ZRT1 | | WN66_02130

[-]

[+]  | gene605 | WN66_00599 | protein_coding | Gene | YCL059C~KRR1~Verified | SGD:S000000564 | Nucleolar protein required for rRNA synthesis and ribosomal assembly; required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit; essential gene | KRR1 | | WN66_00599

[-]

[+]  CAR71 | gene3383 | CAR71 | protein_coding | Gene | potentially novel~GTK30J00210 | | | | | WN66_07046

[-]

[+]  | gene133 | WN66_00133 | tRNA | Gene | tL(UAA)B1 | | | | | WN66_00133

[-]

[+]  | gene1667 | WN66_01645 | protein_coding | Gene | YEL067C~Uncharacterized | SGD:S000000793 | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies | | | WN66_01645

[-]